OptygenHP - The Next-Generation Optygen Formula
First Endurance continues to lead the endurance nutrition category by introducing OPTYGENHP, the next-generation of Optygen. This revolutionary formula is the result of human clinical trials and the latest scientific research on increasing endurance and performance. New features include Beta-Alanine as well the most potent Rhodiola available. The two main adaptogens in OPTYGENHP were first used by Tibetan Sherpas to help them climb Mt. Everest. Optygen and OPTYGENHP utilize these two unique adaptogens because clinical research on elite endurance athletes has shown them to:
Increase oxygen utilization (1)
Increase the body's ability to adapt to high levels of physical stress (1)
Increase aerobic threshold and reduce lactic acid (2)
"Since I started to use Optygen and PreRace in 2007, I've captured all three Grand Tour titles. Based on these results, OpytgenHP and PreRace will certainly continue to be part of my daily racing and training routine."
-Alberto Contador
NOW WITH BETA-ALANINE
Each serving of OPTYGENHP provides 1,000mg Beta-Alanine per serving. Beta-Alanine is supported by wealth of cutting-edge human clinical research showing it increases muscular endurance, boosts strength, improves exercise capacity (so you can exercise longer) and delays muscular fatique (3). The mechanism behind Beta-Alanine works synergistically with the adaptogens, chelated chromium and ATPro in OPTYGENHP, to help endurance athletes maximize performance.
THE MOST POTENT RHODIOLA AVAILABLE
Additionally, First Endurance has sourced the most potent Rhodiola available. The new OPTYGENHP formula contains 5% rosavin and contains 67% more actives than the Rhodiolas in the original Optygen formula. Clinical studies on elite endurance athletes have shown that it is the rosavins in Rhodiola that play a critical role in allowing the body to adapt to high levels of physical stress.
*Daily Value Not Established
Other Ingredients: Glycerine Capsule
Chelavite is a registered trademark of Albion laboratories, Inc.
Covered by Albion international, Inc., U.S. Patent 5,614,553.
Q: How is OPTYGEN-HP different than the original Optygen formula?
A: Beta-Alanine is a beta-amino acid that is a precursor to L-Carnosine in muscle. L-Carnosine is synthesized in muscle when Beta-Alanine is bound to histidine, another amino acid. With intense training, you can increase your carnosine levels with a limiting factor: the body cannot produce enough Beta-Alanine to allow the body to continue to increase carnosine levels. Clinical studies show that supplementing with Beta-Alanine allows the body to produce significantly higher carnosine levels. Through its effect on carnosine levels, beta-alanine synthesizes lactic acid to be re-used as fuel. The result is a highly effective mechanism for the metabolism of lactate, which in-turn improves endurance capacity allowing you to train and race at a higher level.
Q: What is Beta-Alanine and how does it work?
A: Beta-Alanine is an amino acid that interacts directly with the amino acid carnosine to buffer lactic acid. With intense training, you can increase your carnosine levels with a limiting factor: the body cannot produce enough Beta-Alanine to allow the body to continue to increase carnosine levels. Clinical studies show that supplementing with Beta-Alanine allows the body to produce significantly higher carnosine levels. The result is a highly effective mechanism for the metabolism of lactate, which in-turn improves endurance capacity.
Q: What are the benefits of taking Beta-Alanine?
A: Cutting edge human clinical studies show Beta-Alanine supplementation significantly improves muscular endurance, exercise capacity (so you can exercise longer) and total work done. The mechanism supporting Beta-Alanine works synergistically with the adaptogens, chelated chromium and ATPro in OPTYGEN-HP to help endurance athletes maximize performance.
Increases Total Work Done by 13%
Boosts strength
Increases endurance capacity
Improves Ventilatory Threshold
Delays onset of neuromuscular fatigue
Q: What is the itching/tingling I feel after I take Optygen-HP?
A: A very small percentage of athletes will feel an itching or tingling sensation when they first start using Optygen-HP. This tingling is due to the Beta-Alanine. Researchers theorize that it is caused by the activation of dorsal root ganglion (DRG) neurons being activated by Beta-Alanine. In the presence of Beta-Alanine, DRG neurons cause multiple action potentials, whereas in the absence only a single action potentials occur. There is no cause for concern. The tingling & itching called paraesthesia should go away after a week of use. Athletes can also split up their dose to two capsules in the AM and two in the PM which should also help reduce the acute tingling/itching sensation.
Q: Do I have to load with OPTYGEN-HP?
A: No, with the addition of Beta-Alanine and the more potent Rhodiola there is no need to load initially.
Q: How will OPTYGEN-HP help me race better?
A: OPTYGEN-HP is designed to help you through your most intense training and racing and will dramatically improve your training and recovery. The OPTYGEN-HP formula is based on the latest human clinical research. The research has shown the following endurance benefits.
Increases Endurance and Performance
Increased strength
Reduces Lactic Acid
Increases oxygen utilization
Increase in VO2 Max
Increase in Time to Exhaustion
Increases Anaerobic threshold
Improved exercise capacity
Increases Maximal Oxygen uptake
30% - 50% increase in Oxygen Utilization
Increase ratio of ATP by 45% - 55%
Enhances Endurance
Increase in ATP production
Q: How long will it take before I start noticing the benefits of OPTYGEN-HP?
A: You should start experiencing the benefits of OPTYGEN-HP approximately six (6) days after you start.
Q: When should I take OPTYGEN-HP?
A: It is best to take OPTYGEN-HP in the morning with a meal.
Q: How long will a bottle last?
A: OPTYGEN-HP has 120 capsules. With a recommended dose of 4 capsules per day, one bottle lasts 30 days.
Q: Is OPTYGEN-HP legal?
A: First Endurance is committed to developing the most advanced endurance supplements on the market. First Endurance has taken additional measures to assure that our products are safe legal and stimulant free. First Endurance supplements are legal to use in any sporting event governed by the World Anti-Doping Association (WADA), the US anti-doping association (USADA) and by the UCI (Union Cycliste International). One or more of the aforementioned governing bodies govern all US Cycling, International Cycling, US Triathlon and International Triathlon.
Some commonalties among these governing bodies include banned substances which fall into one or more of the following categories as listed in Section I A-E of the UCI Prohibited Classes of substance and Prohibited Methods document. A) Stimulants B) Narcotics C) Anabolic agents D) Diuretics and E) Peptide hormones, mimetics and analogues. This document goes on to list banned substances within each of these classes. Regulations also ban 'Compounds chemically or pharmacologically related to the products mentioned'.
OPTYGEN-HP contains NO ingredients, which are explicitly listed under the banned substance list, nor are any of the ingredients related chemically or pharmacologically. First Endurance has also contacted the USADA and received verbal confirmation that our ingredients are not banned based on their regulations. Note: USADA, WADA and UCI do not offer any certification or written confirmation.
First Endurance manufactures its formulations to the highest GMP (Good Manufacturing Practice) standards available. In addition we use a proprietary manufacturing method for added safety and assurance. Following the Supplement Facts panel you will notice we list 'NO processing aids' under Other Ingredients. The only ingredients found in Optygen, are those listed in the Supplement Facts Panel.
Part XIV Article 7 of the Anti-doping Examination Regulations contains the following warning: riders must refrain from using any substance, foodstuff or drink of which they do not know the composition. It must be emphasized that the composition indicated on a product is not always complete. The product may contain prohibited substances not listed in the composition.
For a complete list of regulations and banned substances please use one of the following links:
Q: What is a "Certificate of Analysis" and why is it important?
A: A Certificate of Analysis (C of A) is a document which states every active and inactive substance used to manufacture a product. A C of A also shows that there are no additional ingredients added to the OPTYGEN-HP formulation. In order to assure the safety and efficacy of OPTYGEN-HP, First Endurance provides a C of A for every lot of OPTYGEN-HP.
Q: Will OPTYGEN-HP help me recover faster?
A: Yes, it will help you recover. Because OPTYGEN-HP will help you adapt during times of maximum stress, it also aids in recovery.
Q: Why are the capsules red?
A: Capsules are dark red, not clear, to further reduce UV light degradation ensuring the highest quality, potency, and purity.
Q: Why is the bottle glass instead of plastic?
A: OPTYGEN-HP is packaged in a blue glass bottle. Unlike plastic bottles, blue glass is an impermeable barrier that protects the product from harmful UV light and oxygen degradation.
Q: Why does OPTYGEN-HP have Cordyceps and Rhodiola Rosea?
A: OPTYGEN-HP utilizes two adaptagens that are the primary ingredients in the formulation. Patented Rhodiola Rosea and Cordyceps are both found and cultivated in Tibet. Both these herbs play critical roles in allowing the body to adapt to high levels of physical stress (similar to the stress a body is subject to when climbing Everest). It's these adaptations to hypoxia (lack of oxygen) which led researchers to also test its effects on elite endurance athletes. Both Rhodiola and Cordyceps have been clinically shown to increase VO2Max, lung function, oxygen utilization and anaerobic threshold significantly.
Q: How should I use Optygen-HP?
A: For best results, use OPTYGEN-HP during all intense training. OPTYGEN-HP will allow you to train at a higher level by improving the body's ability to adapt to physical stress, increasing aerobic threshold and reducing lactic acid. These improvements will help you race at a higher level. For best results, OPTYGEN-HP should be used consistently for many months. If you start taking OPTYGEN-HP a week before a race, benefits will be minimal.
Q: Is it OK to use OPTYGEN-HP everyday even though it has phosphates in the formula?
A: Through its role in 2,3 DPG synthesis, phosphorous may reduce lactate accumulation by enhancing oxygen release to tissues. The clinical research recommends taking 1g of sodium phosphate four times per day for at least three days leading up to a race. Prolonged use at a level of 4g per day may adversely affect calcium absorption. The research clearly indicates that sodium phosphate should be used acutely prior to a race.
OPTYGEN-HP's ATPro matrix is designed to assure Adenosine Tri-Phosphate (ATP) production. All the ingredients in the ATPro matrix play critical roles in ATP formation, including Sodium and Potassium Phosphate. The phosphate levels used in OPTYGEN-HP on their own are not enough to elicit an ergogenic response, nor are they enough to affect PH balance or Calcium absorption.
Q: Are First Endurance products safe from Cross Contamination?
A: Since our primary market is elite endurance athletes we have everything to lose if someone were to test positive and trace it back to our product. Positive tests which have been traced back to supplements are always traced back to a supplement which does not directly market their products to Pro Endurance Athletes. I.E.. The bodybuilding supplements can legally sell androstenedione, DHEA, and precursors. Cross contamination that happens at the manufacturing site is not an issue with these companies. There is a level of tolerance set by the FDA which allows for a certain level of cross contamination. These supplement companies will manufacture an androstene type product, clean the blender and then manufacture an amino acid. The amino acid supplement may contain a small (parts per million) level of androstenedione.
Realize that nothing is absolute. When you purchase any packaged food you have a risk of a contaminated product. Packaged foods, pharmaceutical companies, OTC products and supplements use many of the same ingredient suppliers. IE The cereal you eat in the morning is fortified with vitamins which come from the same supplier of vitamins found in your multivitamin. Some vitamin suppliers also supply pro-hormones. The key is to minimize your risk. First Endurance takes all the available steps to assure there is no cross contamination.
At First Endurance we take all the necessary steps to prevent this.
a) Our manufacturing and packaging facilities do not allow a single banned substance (except caffeine) to enter the facility.
b) First Endurance requires a wet wash between products. FDA approved facilities require a high standard of cleanliness in order to minimize contamination. We take it a step further by requiring the machines, blenders to be cleaned with water.
c) We source ingredients only from manufacturers who DO NOT supply pro-hormones. This eliminates the risk of cross-contamination at the supplier level.
Due to our level of concern, you can feel safer taking our product then your cereal.
In addition, only FDA approved facilities require Certificate's of Analysis. These C of A's, are audited and reviewed by the FDA during their facility audits. A C of A assures that each of those ingredients have been tested for identity and only those ingredients are used in the product. First Endurance is the only supplement company which offers a C of A.
First Endurance - Multi-V
Multi-V INGREDIENTS Use Directions: Take three (3) tablets with your pre-exercise meal.
Supplement Facts
Serving Size: 3 Tablets
Servings per Container: 30
Amount Per Serving
%DV
Vitamin A (100% as beta-carotene)
5,000 IU
100%
Vitamin C (as ascorbic acid and calcium ascorbate)
400mg
670%
Vitamin E (as natural d-alpha tocopherol & mixed tocotrienols)
200 IU
675%
Vitamin B1 (as thiamin)
4 mg
250%
Vitamin B2 (as riboflavin)
5 mg
300%
Niacin (as niacinimide)
20 mg
100%
Vitamin B6 (as pyridoxine hydrochloride)
4 mg
250%
Folate (as folic acid)
400 mcg
50%
Vitamin B12 (as cyanocobalamin)
30 mcg
500%
Biotin
300 mcg
100%
Pantothenic Acid (as d-calcium pantothenate)
20mg
200%
Iodine (as Potassium Iodide)
150mg
100%
Magnesium (as oxide and amino acid chelate)
250mg
65%
Zinc (as oxide and gluconate)
30mg
200%
Selenium (as amino acid chelate)
140mg
200%
Copper (as gluconate)
2mg
100%
Manganese (as gluconate)
2mg
100%
Chromium (as Chelavite® amino acid chelate)
120mcg
100%
Molybdenum (as citrate)
75mcg
100%
Iron (as Ferrocel® amino acid chelate)
18mg
100%
Carbogen Enzyme Blend
160mg
*
Omega 3 Fatty Acids (minimum 45% EPA & DHA)
100mg
*
Oractive Fruit Extracts (Elderberry, Red Grape, Cranberry, Billberry)(guaranteed 8,000 ORAC value)
*Daily Value Not Established **Percent Daily Values are based on a 2,000 calorie diet.
Multi-V™ is the first multinutrient vitamin that's clinically proven to enhance endurance The nutrients in Multi-V have been shown to effectively protect athletes from the stresses of exercise and to improve endurance(1,2,3,4,8,11,12,13). Multi-V is the only multivitamin that contains Carbogen®, a patented enzyme blend that's been shown in clinical studies to improve carbohydrate utilization and increase time to exhaustion significantly (1).
THERE'S NOTHING ELSE LIKE IT
Multi-V is unlike any other multivitamin available. This unparalleled formulation contains a number of special ingredients (besides vitamins and minerals) that address the unique requirements of endurance athletes. In addition to having the highest-quality, most bio-available vitamins and chelated minerals available, this special endurance formula delivers clinically effective doses of Enzymes, Iron, Green Tea, Ginkgo Biloba and Omega-3 Fatty Acids (2,10,11). Multi-V is also formulated with Ferrochel Iron- a highly bioavailable source of Iron which is non-toxic and does not affect the absorption of minerals, like other Iron sources do (4,5,9,10).
PATENTED ENZYME BLEND
Multi-V is the only multivitamin that contains a patented enzyme blend called Carbogen. You won't find Carbogen in any other endurance products. First Endurance has the sole license for Carbogen in the endurance market. Clinical studies on elite cyclists showed Carbogen breaks down multi-chain carbohydrates into simple glucose. This is important for endurance athletes because glucose is readily accessible and useable for working muscles. What's really unique about Carbogen is that even with this fast breakdown of carbohydrates, there is no affect on insulin. With no insulin spike, your blood sugar remains elevated for many hours so it can fuel working muscles and improve performance. A summary of the Clinical Study is found below:
23% increase in blood glucose levels during high intensity exercise
Sustained increase in blood glucose levels for 5 hours
Significant decrease in the accumulation of blood lactate (58% average)
43% increase in time to exhaustion
Decreased rate of perceived exertion (RPE).
ANTIOXIDANT PROTECTION THAT'S SECOND TO NONE
The antioxidant profile in Multi-V is also unequaled. ORAC-Oxygen Radical Absorbance Capacity testing is recognized as the "Gold Standard" for measuring antioxidant protection against oxidative damage (6,7). Multi-V is one of the first products to utilize this important technology to ensure superior antioxidant protection. This new testing method allows nutrients to be qualified in their antioxidant capacity with a number. Multi-V contains some of the highest tested nutrients found with ORAC values of 8,000 units or more and guarantees this with analytical tests. Multi-V contains an antioxidant support blend that includes Bioflavanoids, Turmeric extract, Grape Seed extract and Alpha Lipoic Acid.(3) These antioxidants are widely considered to be the best antioxidants available. This is one of the many ways Multi-V helps protect endurance athletes from the stresses and demands of everyday training and racing.
A: Multi-V is a new Multi-Nutrient formula that provides endurance athletes with endurance specific vitamins, minerals and nutrients needed for endurance exercise training and racing. This formula is unique in that it's the first with ingredients clinically proven to enhance endurance. Multi-V utilizes the latest clinical research on endurance nutrition and input from some of the best endurance athletes in the world.
Q: What are the benefits of using Multi-V daily?
A: The benefits of E3 are:
Improved Performance
Unmatched Antioxidant Protection
Assurance that you are not deficient in any critical nutrients
Full spectrum of Vitamins and Minerals
Reduction in sickness caused by over-training
Most bio-available sources of Nutrients
Q: What is Carbogen and how does it work?
A: Carbogen is the patented enzyme blend in Multi-V. Clinical studies on elite cyclists showed Carbogen breaks down multi-chain carbohydrates into simple glucose. This is important for endurance athletes because glucose is readily accessible and useable for working muscles. What's really unique about Carbogen is that even with this fast breakdown of carbohydrates, there is no affect on insulin. This is important because it doesn't create an insulin spike. Blood glucose remains elevated for many hours. A summary of the Clinical Study is found below:
Significant increase in blood glucose levels during high intensity exercise by 23%
Sustained increase in blood glucose levels for 5 hours
Significant decrease in the accumulation of blood lactate by 58% average
Significant increase in time to exhaustion by 43%
Decreased rate of perceived exertion (RPE).
A clinical trial was performed on the patented enzyme system CARBOGEN from Triarco Industries, Inc. at the University of Dayton Human Performance Lab, Dayton, OH by Janine T. Baer, Ph.D., RD, Associate Professor of Health and Sport Science. The purpose of the study was to investigate the effect of 160 mg of Carbogen® consumed with a meal replacement bar on exercise performance during 60 min of high intensity cycling.
After an overnight 12-hr fast 5 trained, male cyclists (mean VO2 max 70 ml/kg/min) performed two 60-min cycling bouts at 80% VO2 max followed by a sprint at 100% VO2 max. Subjects consumed a meal replacement bar plus either 160 mg Carbogen ? or 160 mg placebo 1 hour prior to each cycling bout. Blood glucose and lactate were determined at: fasting, 1 hr-post feeding, at 30 and 60 minutes of exercise and post-sprint. Glucose levels were consistently higher when Carbogen® was used, with the values after 60-min of exercise significantly higher than the placebo (Carbogen® 73.8+3.6 mg/dl vs. placebo 58.4+ 11.9mg/dl, P<.05) (Graph 1). Lactate values were also consistently lower with the values after 30 min of exercise significantly lower than the placebo (Carbogen® 1.2 + .05 vs. placebo 3.3+0.23, P<.05) (Graph 2). Subjects were able to maintain a 100% VO2 max workload significantly longer with Carbogen® vs. placebo (6.3+3.4 min vs.4.4+ 2.9 min, p<0.001) (Graph 3).Additionally, subjects reported a lower rate of perceived exertion during the exercise trial with Carbogen® (mean RPE 12 + 1.0) vs. placebo (mean RPE 13 + 1.0).
Q: What will Gingko Biloba do for me?
A: The levels of Gingko Biloba in Multi-V have been clinically shown to improve circulation.
Q: What are Chelated Minerals and are they better?
A: Chelatation is a patented process that creates chemical bonds with nutrients like chromium, iron and magnesium. This process makes minerals highly bioavailable. This is important because it ensures the nutrient is bonded with the amino acid chelate is easily absorbed and digested.
Q: What is Iron Amino Acid Chelate and how is that better than other Iron sources?
A: Amino Acid Chelates form a highly stable bio-available bond. Unlike Iron as Ferrous Fumarate, Iron AAC does not compete for the binding sites of some minerals like Calcium. In addition, there are no toxicity issues. This Iron used in Multi-V is highly bio-available and will not diminish your calcium or other minerals. It's also very safe.
Q: There are also vitamins, minerals and antioxidants in Ultragen and E3. Do I still need the Multi-V?
A: The Multi-V is designed to work synergistically with the other First Endurance products. The First Endurance research team reviewed every ingredient in the First Endurance product line to assure you are getting the levels of nutrients you need for endurance training without worrying about the risk of over-dosing with any ingredient. In addition, Multi-V also works great as a stand-alone Multi-Vitamin for your every day needs.
Q: Why isn't there Calcium in Multi-V?
A: Our athletes told us that they did not want to consume more than 3 tablets in their Multi-Vitamin. The addition of Calcium to this formula would have required a 4th tablet to the daily dose. In addition, one serving of Ultragen contains 500mg Calcium and one serving of E3 contains 100mg calcium. On a typical training day athletes who use E3 and Ultragen will consume between 600mg (60% RDA) and 900mg(90% RDA) of Calcium from Ultragen and E3.
Q: Should I use Multi-V in my off training months? Can I use it every day?
A: Yes. The Multi-V is designed to be your daily Multi-Vitamin and should be used every day all year long.
Q: What types of athletes should be taking Multi-V?
A: Any athlete that does endurance exercise and training will benefit from Multi-V. The nutrients in Multi-V have been shown in clinical studies to effectively protect endurance athletes from the stresses of exercise and to improve endurance performance.
Q: What is ORAC and why is this good for me?
A: ORAC=Oxygen Reactive Absorbancy Capacity. ORAC is a quantitative measure of an antioxidants ability to absorb oxidative damage There is clinical data supporting this methodology. ORAC testing is considered the gold standard for measuring antioxidant capacity. This new FDA-approved method of testing antioxidants will become common in the future. Multi-V is one of the first products to use this testing method. This ensures you have antioxidant protection and quality that is second to none. Antioxidants generally range in their ORAC score from 50 to 9,000. An ORAC score of 8,000 found in the Multi-V provides the level of oxidative protection endurance athletes need to protect them from the stresses and demands of every day training.
Q: Should I take Multi-V on days I'm not training?
A: Yes. The Multi-V is designed to be taken every day, just like any other multi-vitamin.
Q: When should I take Multi-V?
A: In order to maximize carbohydrate utilization, it's best to take Multi-V one to two hours before training or racing with your pre-exercise meal. Multi-V can be taken with breakfast, lunch or dinner, depending when you're exercising.
Q: Should I split up the 3 tablet dose into 3 separate meals a day, or should I take this all at once?
A: It's important to take all three tablets all at once in order to get the required dosage of Cargoben, the patented enzyme blend in Multi-V that maximizes carbohydrate utilization.
Q: How many servings are in a container of Multi-V?
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